Preheat your oven to 350°F (175°C) and lightly grease a 9x5 inch loaf pan. This simple step ensures your beautiful bread won't stick!
Carefully separate each biscuit and then slice each one in half lengthwise. You'll end up with 16 smaller biscuit pieces, perfect for layering.
In one small bowl, melt the butter until smooth. In a separate bowl, stir together the 1 cup granulated sugar and 2 teaspoons pumpkin pie spice. For your delicious pumpkin filling, combine the pumpkin puree, brown sugar, and the remaining ½ teaspoon pumpkin pie spice in a third small bowl, mixing until everything is well combined.
Take one biscuit half, dip it briefly into the melted butter, then gently dredge it in the sugar-spice mixture until coated. Next, spread about 1 to 2 teaspoons of the pumpkin filling onto one side of the coated biscuit.
Place the prepared biscuit piece in your greased loaf pan, leaning it against one side. Continue this process with all the remaining biscuit pieces, stacking them neatly in the pan to create your "pull-apart" loaf.
Pop the loaf pan into your preheated oven and bake for 40 to 45 minutes. Look for a gorgeous golden brown color on top. If it starts browning too quickly, you can lightly cover it with aluminum foil.
Once baked, remove the bread from the oven and let it cool completely in the pan on a wire rack. This is an important step to allow the bread to set before glazing.
In a small bowl, whisk together the powdered sugar, 1 tablespoon of milk, and vanilla extract until you have a smooth, creamy glaze. If it seems too thick, add the second tablespoon of milk, a little at a time, until it reaches a perfect drizzle consistency.
Generously drizzle the sweet vanilla glaze over your cooled pumpkin pull-apart bread. Now it’s ready to tear apart and savor every cozy bite!